The entire length of the i-81 covers a distance of aprox. 846 miles.
It takes approx. 14 hrs. and 2 minutes to travel the 846 mile length with
a sustained driving speed averaging 60 mph.
When including sleep/rest/eating time; a more leisurely drive covering the
entire 846 mile distance consumes closer to 30 hrs.
The i-81 route across the eastern US is shown in the map above.
State Driving Distances ...